10 Most Lucrative Businesses to Open in Missouri in 2023

As we look towards the future, Missouri is fast becoming a hub for innovation and entrepreneurial endeavors. With its booming economy and diverse population, the state offers abundant opportunities for those seeking to start their own businesses.

In this article, we will explore the 10 most lucrative businesses to open in Missouri in 2023. Our list includes technology startups, healthcare facilities, food and beverage industry ventures, renewable energy companies, and home services providers.

We have carefully analyzed data to identify these sectors as those with the greatest potential for growth in Missouri over the next few years. Whether you are an experienced entrepreneur or just starting out on your business journey, there is something for everyone on this list.

So let’s dive in and discover which industries are poised to make a major impact in Missouri’s economy!

One of the thriving industries in Missouri in 2023 is setting up your own business, such as by filing an LLC in Missouri. Understanding how to file an LLC in missouri can provide aspiring entrepreneurs with the necessary legal framework to start their lucrative venture in the state.

One booming opportunity for ambitious freelancers in Missouri exists due to the rising demand for specialized services. Setting up a Missouri LLC can provide freelancers with the perfect platform to explore different sectors and benefit from tailored missouri LLC services for freelancers.

If you’re considering entering the Missouri business scene, exploring the best businesses to start in missouri should be your first step to success in 2023.

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Technology Startups

If you’re looking to make a name for yourself in Missouri’s business scene, you should definitely consider starting a tech startup. The state has a thriving entrepreneurial ecosystem that fosters innovation and encourages startups to grow and succeed. In addition, there are funding resources available for new businesses, including angel investors and venture capitalists.

Missouri’s technology sector is rapidly expanding, with numerous successful startups emerging from the state in recent years. This is due in part to the availability of talented workers who’ve graduated from top universities such as Washington University in St. Louis and the University of Missouri-Columbia. These individuals bring their skills and knowledge to local startups, helping them achieve success.

Starting a tech startup in Missouri could be your ticket to financial success. With support from the state’s entrepreneurial ecosystem and access to funding resources, you’ll be well positioned to take advantage of this growing industry.

However, if technology isn’t your thing, another option worth exploring is healthcare facilities – read on to learn more about this lucrative opportunity.

Starting a tech startup in Missouri presents an exciting opportunity for entrepreneurs looking to combine creativity with innovation while potentially earning big bucks. With access to funding resources and support from the state’s entrepreneurial ecosystem, success is within reach for those willing to take the leap.

However, if technology isn’t your area of interest or expertise, there are other lucrative businesses worth considering – specifically healthcare facilities which we will explore further next.

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Healthcare Facilities

Running healthcare facilities can be a fulfilling and impactful way to serve the community. In Missouri, the healthcare industry is thriving as a result of its growing population, which has led to increased demand for quality medical services.

Here are three lucrative business opportunities in the healthcare sector that entrepreneurs should consider venturing into:

1) Medical Tourism – With world-class medical facilities and affordable healthcare services, Missouri is becoming a popular destination for medical tourism. Entrepreneurs can tap into this market by investing in businesses such as hotels or transportation services that cater specifically to medical tourists.

2) Senior Care Facilities – As baby boomers age, there is an increasing demand for senior care facilities in Missouri. This presents an opportunity for entrepreneurs looking to invest in long-term care facilities or nursing homes that provide specialized care for seniors.

3) Healthcare Information Technology (HIT) – The use of technology in healthcare has become increasingly important over the years. HIT companies develop software solutions that help hospitals and other healthcare providers manage patient data more efficiently. Entrepreneurs with experience in tech may find this sector particularly appealing.

As the population continues to grow and people seek out better health outcomes, these businesses have great potential for success. However, it’s important to keep abreast of industry trends and regulations to ensure compliance with state laws governing these types of businesses.

Moving onto our next subtopic about the food and beverage industry…

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Food and Beverage Industry

As we explore the next most lucrative business opportunities in Missouri, we can’t overlook the food and beverage industry.

With a growing ‘foodie’ culture in the state, there’s ample opportunity to tap into this market and meet the demands of consumers.

Additionally, businesses in this sector can benefit from various state incentives tailored for food and beverage enterprises.

Entrepreneurs can also explore opportunities in craft beer and distilling, which’ve seen significant growth in recent years.

Tap into Missouri’s Growing Foodie Culture

Don’t miss out on the delicious opportunity to tap into Missouri’s thriving foodie culture and satisfy your entrepreneurial cravings.

The state has seen a rise in demand for farm-to-table concepts and culinary tourism, making it an ideal destination for those looking to venture into the food and beverage industry. With an abundance of locally-sourced ingredients, Missouri is a prime location for businesses that focus on sustainable practices.

Here are four reasons why tapping into Missouri’s foodie culture could be a lucrative move:

  • Culinary tourism is on the rise, with visitors seeking local experiences and flavors.
  • The state’s agricultural industry provides a wealth of fresh produce, meats, and other ingredients.
  • Consumers are increasingly interested in supporting small businesses that prioritize sustainability.
  • Food halls and markets have become popular gathering places for locals and tourists alike.

By capitalizing on these trends, entrepreneurs can benefit from state incentives for food and beverage businesses.

Benefit from State Incentives for Food and Beverage Businesses

You can take advantage of state incentives for food and beverage businesses in Missouri to boost your profits and expand your reach. Missouri offers a range of programs designed to support local businesses, including tax breaks and grants. These incentives are specifically tailored to the food and beverage industry, making it easier for entrepreneurs to get started and stay competitive.

To give you an idea of what’s available, here’s a brief overview of some of the most popular programs:

Program Description Eligibility
Missouri Agricultural and Small Business Development Authority (MASBDA) Low-interest loans for small businesses in agriculture, forestry, or food production Must be a Missouri resident with less than 100 employees
Neighborhood Assistance Program (NAP) Tax credits for donations made to approved community development projects, such as urban agriculture initiatives or farmers’ markets Businesses that donate at least $1,000

By taking advantage of these programs, you can not only save money on startup costs but also help boost the local economy by supporting Missouri’s thriving food and beverage industry. As we’ll see in the next section, there are plenty of opportunities to explore in craft beer and distilling – two areas where state incentives have helped spur growth in recent years.

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Explore Opportunities in Craft Beer and Distilling

If you’re a fan of locally-made craft beer and spirits, Missouri offers a wealth of opportunities to explore the unique flavors and experiences that come with these small-batch products. Here are three reasons why exploring craft beer and distilling in Missouri can be a lucrative business venture:

  1. Craft Beer Tourism: According to the Brewers Association, craft breweries contributed $83 billion to the U.S. economy in 2019, with more than 25% of those sales coming from taproom and brewpub sales. Missouri has over 140 craft breweries, offering visitors a chance to taste unique local flavors while supporting small businesses. With the rise of experiential travel trends like food tourism, there’s also an opportunity for breweries to collaborate with local restaurants or offer brewery tours as part of their business model.
  2. Distillery Collaborations: Similar to craft beer collaborations between breweries, distilleries can benefit from working together on product development or co-branding opportunities. For example, partnering with local wineries or using regional ingredients like corn or rye can help differentiate a distillery’s offerings from competitors. Additionally, many states have laws that allow for direct-to-consumer sales at distilleries, which can boost revenue streams.

As Missouri continues to foster its reputation as a hub for craft beverages, entrepreneurs should consider exploring opportunities in this growing industry. However, another area where businesses could find success is renewable energy solutions – let’s take a closer look at how this sector is shaping up in Missouri next.

Renewable Energy

Renewable energy is the future, and investing in it now can bring not only profits but also contribute to a sustainable future for Missouri. Green investments are becoming increasingly popular as consumers become more environmentally conscious, and businesses must adapt to cater to these new demands. Sustainable solutions are being sought after by both individual consumers and larger corporations alike.

The economics of going green are also worth examining as renewable energy becomes more viable in Missouri’s business landscape. Solar panels, wind turbines, and hydroelectric power plants can all provide alternative sources of energy that reduce the need for traditional fossil fuels. In addition, many renewable energy projects can receive tax incentives and grants from the state government.

Missouri has already made significant strides towards embracing renewable energy with initiatives such as the Missouri Renewable Energy Standard. This requires investor-owned utilities to generate at least 15 percent of their electricity from renewable resources by 2021. As a result, there is a growing need for businesses that specialize in renewable energy technologies such as solar panel installation or wind turbine maintenance. The potential for growth in this sector is immense, making it an attractive option for entrepreneurs looking to capitalize on sustainability trends.

As we look towards the future of business opportunities in Missouri, another promising sector is home services. Nonetheless, incorporating sustainable practices into these industries will be crucial in meeting consumer demand while reducing environmental impact.

Home Services

Homeowners in Missouri can benefit from incorporating sustainable practices into their home services, such as using energy-efficient appliances and reducing water waste. With the rising popularity of DIY trends, more and more homeowners are looking for ways to make their homes eco-friendly on a budget. This presents an excellent opportunity for entrepreneurs who specialize in green home services.

One area of focus that has seen significant growth is landscaping services. Homeowners are increasingly interested in creating sustainable outdoor spaces that require less maintenance and use fewer resources. Entrepreneurs who offer eco-friendly landscaping services, like xeriscaping or rain gardens, can tap into this growing market while also promoting environmental stewardship.

Another lucrative business idea within the realm of home services is offering consulting or installation services for energy-efficient upgrades. From solar panels to smart thermostats, there are many options available for homeowners looking to reduce their carbon footprint and save money on utility bills. By staying up-to-date with the latest technology trends and partnering with reputable suppliers, entrepreneurs can position themselves as experts in this field and attract a loyal customer base.

The home services industry offers numerous opportunities for environmentally conscious entrepreneurs to capitalize on DIY trends and promote sustainable practices. Whether it’s through offering eco-friendly landscaping options or providing consulting services for energy-efficient upgrades, there is a growing demand among Missouri homeowners for green solutions that prioritize both cost savings and environmental responsibility. As innovation continues to drive this industry forward, those who stay ahead of the curve will be well-positioned for success in 2023 and beyond.


In conclusion, Missouri is a state with abundant business opportunities for entrepreneurs looking to establish themselves in the market. The top 10 most lucrative businesses to open in Missouri in 2023 include technology startups, healthcare facilities, food and beverage industry, renewable energy, and home services.

While the data-driven analysis of these businesses can give us an idea of their potential profitability and growth rate, it’s important to note that success ultimately depends on factors such as market demand, competition, and management skills. Entrepreneurs should carefully evaluate these factors before investing their time and resources into these industries.

As the economy continues to evolve and new trends emerge, there may be other businesses that will become more profitable than those listed here. However, by staying informed about industry trends and understanding the needs of consumers in their local area, entrepreneurs can position themselves for success in any industry they choose to pursue.

Ultimately, with hard work and dedication to their craft, anyone can succeed as an entrepreneur in Missouri.

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